The protective effect of Phyllanthus emblica Linn. extract against doxorubicin-induced hepatotoxicity in rats

Recently many researches have been carried out on Malacca fruit extract and its potential protective effect in vivo organ toxicity. However, there is still no research the of ( Phyllanthus emblica L.) induced hepatotoxicity anticancer drugs, especially doxorubicin rats. The objective this study to determine ethanol P. against doxorubicin-induced A preliminary phytochemical test was done followed by administration into Histological studies were observe liver tissue. Phytochemical results show that contains flavonoids, phenols, tannins, triterpenoids, terpenoids, alkaloids. increasing value ALT ALP tissue proved toxicity caused doxorubicin. L . at dosage 200 mg/kg BW 400 rats successfully played as an antioxidant decrease ALPvalues improve normal hepatocytes more dominant than lysis less mark bleeding congestion blood vessels.